| 04/24/2021 | Nationals | Marlins | 10:00AM - 12:00PM | C.M.S. Little League Complex / Henderson Field | |
| 04/24/2021 | Athletics | Brewers | 10:00AM - 12:00PM | C.M.S. Little League Complex / Linquist Field | |
| 04/28/2021 | Marlins | Athletics | 5:30PM - 7:30PM | C.M.S. Little League Complex / Henderson Field | |
| 04/28/2021 | Blue Jays | Brewers | 5:30PM - 7:30PM | C.M.S. Little League Complex / Linquist Field | |
| 05/01/2021 | Nationals | Brewers | 11:00AM - 1:00PM | C.M.S. Little League Complex / Henderson Field | |
| 05/01/2021 | Blue Jays | Marlins | 11:00AM - 1:00PM | C.M.S. Little League Complex / Linquist Field | |
| 05/01/2021 | TBD | Athletics | 1:30PM - 3:30PM | C.M.S. Little League Complex / Henderson Field | |
| 05/04/2021 | Athletics | Marlins | 5:30PM - 7:30PM | C.M.S. Little League Complex / Henderson Field | |
| 05/04/2021 | Blue Jays | Nationals | 5:30PM - 7:30PM | C.M.S. Little League Complex / Linquist Field | |
| 05/06/2021 | Blue Jays | Brewers | 5:30PM - 7:30PM | C.M.S. Little League Complex / Henderson Field | |
| 05/06/2021 | Nationals | Athletics | 5:30PM - 7:30PM | C.M.S. Little League Complex / Linquist Field | |
| 05/08/2021 | Athletics | Nationals | 10:00AM - 12:00PM | C.M.S. Little League Complex / Henderson Field | |
| 05/08/2021 | Marlins | Brewers | 10:00AM - 12:00PM | C.M.S. Little League Complex / Linquist Field | |
| 05/08/2021 | TBD | Blue Jays | 12:30PM - 2:30PM | C.M.S. Little League Complex / Henderson Field | |
| 05/11/2021 | Athletics | Blue Jays | 5:30PM - 7:30PM | C.M.S. Little League Complex / Henderson Field | |
| 05/13/2021 | Brewers | Nationals | 5:30PM - 7:30PM | C.M.S. Little League Complex / Henderson Field | |
| 05/13/2021 | Marlins | Blue Jays | 5:30PM - 7:30PM | C.M.S. Little League Complex / Linquist Field | |
| 05/15/2021 | Marlins | Nationals | 10:00AM - 12:00PM | C.M.S. Little League Complex / Henderson Field | |
| 05/15/2021 | Blue Jays | Athletics | 10:00AM - 12:00PM | C.M.S. Little League Complex / Linquist Field | |
| 05/15/2021 | TBD | Brewers | 12:30PM - 2:30PM | C.M.S. Little League Complex / Henderson Field | |
| 05/18/2021 | Blue Jays | Nationals | 5:45PM - 7:45PM | C.M.S. Little League Complex / Henderson Field | |
| 05/20/2021 | Brewers | Blue Jays | 5:45PM - 7:45PM | C.M.S. Little League Complex / Henderson Field | |
| 05/20/2021 | Athletics | Marlins | 5:45PM - 7:45PM | C.M.S. Little League Complex / Linquist Field | |
| 05/22/2021 | Marlins | Blue Jays | 10:00AM - 12:00PM | C.M.S. Little League Complex / Henderson Field | |
| 05/22/2021 | Brewers | Athletics | 10:00AM - 12:00PM | C.M.S. Little League Complex / Linquist Field | |
| 05/22/2021 | TBD | Nationals | 12:30PM - 2:30PM | C.M.S. Little League Complex / Henderson Field | |
| 05/25/2021 | Marlins | Brewers | 5:45PM - 7:45PM | C.M.S. Little League Complex / Henderson Field | |
| 05/25/2021 | Nationals | Athletics | 5:45PM - 7:45PM | C.M.S. Little League Complex / Linquist Field | |
| 05/27/2021 | Brewers | Marlins | 5:45PM - 7:45PM | C.M.S. Little League Complex / Henderson Field | |
| 05/29/2021 | Brewers | Athletics | 10:00AM - 12:00PM | C.M.S. Little League Complex / Henderson Field | |
| 05/29/2021 | Nationals | Blue Jays | 10:00AM - 12:00PM | C.M.S. Little League Complex / Linquist Field | |
| 05/29/2021 | TBD | Marlins | 12:30PM - 2:30PM | C.M.S. Little League Complex / Henderson Field | |
| 05/31/2021 | Nationals | Marlins | 5:45PM - 7:45PM | C.M.S. Little League Complex / Henderson Field | |
| 05/31/2021 | Athletics | Blue Jays | 5:45PM - 7:45PM | C.M.S. Little League Complex / Linquist Field | |
| 06/02/2021 | Brewers | Nationals | 5:45PM - 7:45PM | C.M.S. Little League Complex / Henderson Field | |
| 06/07/2021 | #4 or #5 Seed | #1 Seed | 5:45PM - 7:45PM | C.M.S. Little League Complex / Henderson Field | |
| 06/07/2021 | #3 Seed | #2 Seed | 5:45PM - 7:45PM | C.M.S. Little League Complex / Linquist Field | |
| 06/08/2021 | #2 Seed | #3 Seed | 5:45PM - 7:45PM | C.M.S. Little League Complex / Linquist Field | |
| 06/08/2021 | #1 Seed | #4 or #5 Seed | 5:45PM - 7:45PM | C.M.S. Little League Complex / Henderson Field | |
| 06/10/2021 | #4 or #5 Seed | #1 Seed | 5:45PM - 7:45PM | C.M.S. Little League Complex / Henderson Field | |
| 06/10/2021 | #3 Seed | #2 Seed | 5:45PM - 7:45PM | C.M.S. Little League Complex / Linquist Field | |
| 06/12/2021 | Lower Seed | Higher Seed | 10:00AM - 12:00PM | C.M.S. Little League Complex / Henderson Field | |
| 06/13/2021 | Higher Seed | Lower Seed | 12:00PM - 2:00PM | C.M.S. Little League Complex / Henderson Field | |
| 06/15/2021 | Lower Seed | Higher Seed | 5:45PM - 7:45PM | C.M.S. Little League Complex / Henderson Field | |